The idea of a church at Åmsele was first raised at a parish meeting in 1856, prompted by the distance villagers had to travel to attend services elsewhere. Land for a burial ground was set aside in 1865, and once funding was secured, building work began in the autumn of 1872. The timber church was raised by master builder Johan Lundström, following designs by Carl Bergström, a floating inspector by trade. It was completed in 1874, with the tower added the following year, and the church was consecrated by vicar Lindfors that same year.
The building is a simple, late example of neoclassical style, with a rectangular nave and a narrower, lower chancel that also houses the sacristy. The church runs north to south, with its sturdy square tower to the north and the chancel to the south. The tower is topped with a square lantern and cross. Inside, the nave has a coved ceiling, while the chancel is covered by a barrel vault.
A restoration took place in 1926. As part of this work, a new altarpiece by the artist Leander Engström was installed, replacing or complementing earlier furnishings. Among the church's older fittings is a pewter wafer box dating from 1761, made by Johan Gustav Ryman.
The church's first organ was built by a local farmer, Johan Vincent Lundström of Åmsele, who is also credited with making the pulpit — a notable example of local craftsmanship contributing directly to the church's fabric. That instrument was replaced by a new organ in 1937.